Senior Associate Scientist-genomics Job in Syngene International Limited

JOB DESCRIPTION

Designation: SeniorAssociate Scientist-Genomics

Job Location: Bangalore

Department: Discovery Biology

About Syngene

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Job Purpose

We are seeking an outstanding scientist with a strong background in Immunoassay and Cell based assays.

Key Responsibilities:

• Performing ELISA, Luminex and ELISPOT based assays.

• Firm understanding of the principles and cell types of the immune system.

• Experience at isolation of PBMCs from the human whole blood.

• Good working knowledge of isolation and enrichment of human (and/or mouse) primary immune cells (T cells, B cells, NK cells, Macrophages etc).

• Sound knowledge of Multicolour flowcytometry based immune phenotyping (highly preferred).

• Well verse with cell viability, proliferation and cytotoxicity (ADCC, CDC) assays.

• Good working knowledge on cytokine release assays (both intracellular and soluble formats).

• Binding and phagocytosis assays.

• Experience at culturing human primary T cells, NK cells, Macrophages.

• Experience at transfection and/or transduction of Primary cells (T cells) and cell lines.

• Experience at culture, propagation and maintenance of cell lines of various origins.

• Excellent attention to experimental details, data documentation and clear communication ofcompiled data.

• Excellent verbal/written communication and ability to communicate effectively with high transparency is essential.

• Follow environment, health, and safety (EHS) requirements at all times in the workplace ensuring individual and lab/plant safety

• Attend training on environment, health, and safety (EHS) measures imparted company

Educational Qualification:

• M.Sc. / M.Tech in Biotechnology, Biology, Biochemistry, Biomedical sciences

Technical/functional Skills:

• Experience with multicolour flow cytometry and data analysis, cytotoxicity, cell proliferation, apoptosis, cell cycle assays.
• Experience in working with mouse primary immune cells, harvesting and generating mouse DCs, macrophages, T cells and B cells.
• ELISA, Luminex and ELISPOT based assays.
• Experience with antibody affinity characterization using Octet and Biacore.
• DNA/RNA extraction, western blotting, PCR.

Experience:

6-10years of experience post qualification.

Behavioral Skills:

• Ability to manage a team of professionals to deliver quality work within the time frame, train and coach junior scientists, inculcate good work ethics.
• Abilitytoworkwithco _x0090_workersandoutsideagenciesprofessionallyandtactfully.
• Excellent verbal/written communication and ability to communicate effectively with high transparency is essential.
• Interpersonal skills with an emphasis on working in a team environment to accomplish impactful results.

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.