Biotech - R & D Job in Zydus Lifesciences Limited

Sr. Scientist (Protein characterization):

Ph. D / M.Sc. / M. Tech. (Biochemistry / Biotechnology) with at least 10 - 12 years of industrial hands-on experience in protein characterization including HPLC, structural, electrophoretic and biochemical techniques. Experience in establishing global biosimilar programs preferred. Sound knowledge in analytical method development, validation and scientific report writing skills.

Senior Scientific Officer / Research Associate / Associate Research Scientist (Protein characterization): PhD / M.Sc. / M. Tech. (Biochemistry/ Biotechnology/ Life sciences) with 0 - 4 years experience in protein analytics including HPLC, structural, biochemical and electrophoretic techniques OR Biologics QA experience in quality management systems (QMS) and compliance. Good communication and report writing skills.

Sr. Scientific Officer/Research Associate/Sr. Research Associate (Upstream Process):

M.Sc. (Microbiology/Biochemistry/Biotechnology)/ M. Tech. with Biotechnology with 1 to 3 years of hands-on experience in upstream operations like handling mammalian cell culture process and microbial fermentation. Handling equipment such as Bioreactors, CEDEX Bioanalyzer, etc. Capable of performing activities such as handling of mammalian cell lines, cell bank preparation, media scouting and process optimization at shake flasks, small-scale bioreactors and pilot scale bioreactors to improve yields & product quality. Good Documentation skills like SOP, STP etc.

Scientist/Principle Scientist (Upstream Process): Ph.D., (Microbiology/Biochemistry/Biotechnology)/ M. Tech. in Biotechnology with more than 10 years of experience. Hands-on experience with upstream process development and process characterization of mammalian and microbial culture. Sound scientific knowledge as well as report writing skills like Process Development Report, Technology Transfer Document and scale up. Should have proven track record to lead a sizeable team.

Sr. Scientific Officer/Research Associate/Sr. Research Associate (In-process analysis and stability group): Ph.D., M.Sc., M. Tech, M. Pharm Biotechnology / Biochemistry or equivalent with 3 10 Years of Experience. Candidate should have hands-on experience on HPLC, gel electrophoresis, spectrophotometric, structural and biochemical techniques for biosimilar or novel biological products. Candidate is responsible for development and qualification of analytical methods, in-process analysis during upstream, downstream and drug product process development, degradation / stability studies, excipient analysis, report and protocol writing.

Sr. Scientific Officer/Research Associate/Sr. Research Associate (Formulations Group): Ph.D., M.Sc., M. Tech, M. Pharm Biotechnology / Biochemistry or with 3 5 Years of Experience. Candidate is responsible for planning and execution of formulation development, stability / degradation studies and technology transfer for biosimilar and novel biological products. Candidate should have hands-on experience on techniques related to liquid and lyophilized formulation development. Candidate is responsible for formulation screening studies, selection of container-closure systems, analysis for formulation screening, stability/degradation studies and documentation.

(Cell line Development):

Molecular Biology (Clone Development):

M. Sc. in any field of life sciences with 3-4 years of experience / Ph.D. in life sciences with hands on experience in molecular biology techniques like PCR, Real-time PCR, Nucleic acid isolation, rDNA techniques, DNA sequencing, in-vitro transcription and in-vitro translation and basic DNA / RNA / Protein analytic tools. Basic knowledge of bioinformatics to handle Molecular Biology analysis tools. Candidate is required to have good communication and scientific report writing skills.

Mammalian Cell Culture:

M.Sc.(Any Life sciences area) /M.tech / M.Pharm with Biotechnology with 3-5 years of experience in mammalian cell culture such as handling of various cell lines, optimization & execution of stable/ transient transfections, clone screening, media/process optimization at shake flasks & small scale bioreactors to improve yields & quality, cell bank preparations, ELISAs. Basic understanding of DoE tools for media optimizations.

Upstream analytics:

M.Sc. (Any Life sciences area) / M. Tech (Biochemistry/Biotechnology)/M. Pharm with Biotechnology years with 2-4 years experience in protein binding studies using SPR, protein characterization techniques like HPLC, HP-SEC, IEF, IEC, SDS PAGE etc for characterization of Biologics

(Immunoassays):

PK/ PD/ Immunogenicity:MSc. (Any life sciences area) / M. Pharm (Biotechnology/Pharmacology) with 3-7 years of experience in activities like development, validation & execution of PK/ PD/ Immunogenicity/ Nab assays (ELISA/CLIA/MSD) to support pre-clinical & clinical studies for Biosimilar /New Biologics in a GLP set up, Experience in animal handling, preparation of regulatory documents. Should have scientific understanding of PK/PD/ADA of biologics in animals & humans; basic knowledge of biostatistics.

Sr. Scientific Officer/ Research Associate/ Sr. Research Associate (Drug Discovery/ oncology/ immunologist):

Ph.D. or M. Sc. (Immunology/ Microbiology/ Biotechnology/ Biochemistry/ CellBiology/ Biochemical Engineering) with more than 0 to 5 years of hands-on experience in immunology assay development, Cell culture expertise, Transfection, small scale upstream and downstream operation handling, purification of recombinant proteins, process characterization and protein analysis. Should have deep knowledge of immunology specifically in immunooncology and validation with good communication and scientific report writing skills and proven track record to lead a sizeable team. Will support strategic planning for initiation and execution of novel biologic drug development programs in oncology, immuno-oncology and inflammation area.